Publications

Peer-Reviewed Manuscripts

38. Champagne AA, Zuleger TM, Warren SM, Smith DR, Lamplot JD, Xerogeanes JW, Slutsky-Ganesh AB, Jayaram P, Patel JM, Myer GD, Diefuss JA (2024) Integrated voxelwise normalization and 3D anatomical mapping automates the quantitative assessment of bone contusions and superficial articular cartilage lesions following anterior cruciate ligament surgery. Journal of Orthopaedic Research. (Link)

37. Hasson M, Fernandes LM, Solomon H, Pepper T, Huffman NL, Pucha SA, Bariteau JT, Kaiser JM, Patel JM (2024) Considering the cellular landscape in marrow stimulation techniques for cartilage repair. Cell Tissues Organs. (Link)

36. Pucha SA, Hasson M, Solomon H, McColgan GE, Robinson JL, Vega SL, Patel JM (2024) Revealing Early Spatial Patterns of Cellular Responsivity in Fiber-Reinforced Microenvironment. Tissue Engineering Part A. (Link) (BioRxiv).

35. Brackin RB, McColgan GE, Pucha SA, Kowalski MA, Drissi H, Doan TN, Patel JM (2023) Improved Cartilage Protection with Low Molecular Weight Hyaluronic Acid Hydrogel. Bioengineering. 10(9):1013. (Link)

34. Brown DM, Yu J, Kuma P, Paulus QM, Kowalski MA, Patel JM, Kane MA, Ethier CR, Pardue MT (2023) Exogenous all-trans retinoic acid induces myopia and alters scleral biomechanics in mice. Investigative Ophthalmology & Visual Science. 64(5):22. (Link)

33. Lemmon EA, Bonnevie ED, Patel JM, Miller LM, Mauck RL (2023) Transient Inhibition of Meniscus Cell Migration Following Acute Inflammatory Challenge. Journal of Orthopaedic Research. 41(9):2055-2064. (Link)

32.   Kim SG, Song J, Ryplida B, Jo HJ, Jeong GJ, Kang IY, Patel JM, Jin EJ, Jang YC, Park SY (2023) Touchable Electrochemical Hydrogel Sensor for Detection of Reactive Oxidative Species-induced Cellular Senescence in Articular Chondrocytes. Advanced Functional Materials. 2213887. (Link)

31. Brown DM, Kowalski MA, Paulus Q, Kumar P, Yu J, Kane MA, Patel JM, Ethier CR, Pardue MT (2022) Altered structure and function of murine sclera in form-deprivation myopia. Investigative Ophthalmology & Visual Science. 63(13):13. (Link)

30. Desai S, Dooner M, Newberry J, Twomey-Kozak J, Molino J, Trivedi J, Patel J, Owens B, Jayasuriya C (2022) Stable human cartilage progenitor cell line stimulates healing of meniscus injuries and attenuates post-traumatic OA changes. Frontiers in Biotechnology and Bioengineering. 10:970235. (Link)

29. Driscoll K, Butani MS, Gultian KA, McSweeny A, Patel JM, Vega SL (2022) Plant Tissue Parenchyma and Vascular Bundles Selectively Regulate Stem Cell Mechanosensing and Differentiation. Cellular and Molecular Bioengineering. 15(5):439-450. (Link)

28. Kowalski MA, Fernandes LM, Hammond KE, Labib S, Drissi H, Patel JM (2022) Cartilage-Penetrating Hyaluronic Acid Hydrogel Preserves Tissue Content and Reduces Chondrocyte Catabolism. Journal of Tissue Engineering and Regenerative Medicine. 16(12):1138-1148. (bioRxiv) (Link)

27. Kandel S, Querido W, Falcon JM, Zlotnick HM, Locke RC, Stoeckl B, Patel JM, Patil CA, Mauck RL, Pleshko N (2022) In Situ Assessment of Porcine Osteochondral Repair Tissue in the Visible-Near Infrared Spectral Region. Frontiers in Bioengineering and Biotechnology. 10:885369. (Link)

26. Patel JM, Haut Donahue TL, Galbusera F, Drew BH, Seitz AM (2022) Editorial: Post-Traumatic Osteoarthritis After Meniscus Injury. Special Issue for Frontiers in Bioengineering and Biotechnology. 10:893800. (Link)

25. Patel JM (2022) Impediments to Meniscal Repair: Factors at Play Beyond Vascularity. Frontiers in Bioengineering and Biotechnology. 10:843166. (Link)

24. Falcon JM, Kandel S, Querido W, Morman J, Patel J, Miller LM, Mauck RL, Pleshko N (2022) Near Infrared Spectroscopic Assessment of Engineered Cartilage for Implantation in a Pre-clinical Model.  Journal of Cartilage and Joint Preservation. 2(1):100038. (Link)

23. Bansal S, Meadows KD, Miller LM, Saleh KS, Patel JM, Stoeckl BD, Lemmon EA, Hast MW, Hast MW, Zgonis MH, Scanzello CR, Elliot DM, Mauck RL (2021) Six Month Outcomes of Clinically Relevant Meniscal Injury in a Large Animal Model. Orthopaedic Journal of Sports Medicine. 9(11):23259671211035444. (Link)

22. Zlotnick HM, Locke RC, Stoeckl BD, Patel JM, Gupta S, Browne KD, Koh J, Carey JL, Mauck RL (2021) Marked differences in local bone remodeling in response to different marrow stimulation technique in a large animal. European Cells & Materials. 19(41):546-557. (BioRxiv) (Link)

21.  Bansal S, Floyd ER, Kowalski MA, Aikman E, Elrod P, Burkey K, Chahla J, LaPrade RF, Maher SA, Robinson JL, Patel JM (2021) Meniscal Repair: The Current State and Recent Advances in Augmentation. Journal of Orthopaedic Research. 39(7):1368-1382. (Link)

20.  Patel JM, Loebel C, Saleh KS, Wise BC, Bonnevie ED, Miller LM, Carey JL, Burdick JA, Mauck RL (2021) Stabilization of Damaged Cartilage with Hydrogel-Mediated Reinforcement and Sealing. Advanced Healthcare Materials. 10(10):e2100315. (Link)

19.  Martin AR, Patel JM, Locke RC, Eby MR, Saleh KS, Davidson MD, Sennett ML, Zlotnick HM, Chang AH, Carey JL, Burdick JA, Mauck RL (2021) Nanofibrous Acellular Hyaluronic Acid Scaffold with Embedded TGF-β3 and SDF-1α for Articular Cartilage Repair in a Large Animal Model. Acta Biomateriala. 126:170-182. (Link)

18.  Sennett ML, Friedman JM, Ashley BS, Stoeckl BD, Patel JM, Alini M, Cucchiarini M, Eglin D, Madry H, Mata A, Semino C, Stoddart M, Moutos FT, Estes BT, Guilak F, Mauck RL, Dodge GR (2021) Long term outcomes of biomaterial-mediated repair of focal cartilage defects in large animal model. European Cells and Materials. 41:40-51. (Link)

17.  Wei Y, Luo L, Gui T, Yu F, Yan L, Yao L, Zhong L, Yu W, Han B, Patel JM, Beier F, Shao Z, Han L, Mauck RL, Tsourkas A, Ahn J, Cheng Z, Qin L (2021) Targeting Cartilage EGFR Pathway for Osteoarthritis Treatment. Science Translational Medicine. 13(576):eabb3946. (Link)

16.  Patel JM*, Sennett ML*, Martin AR, Ashley BS, Eby MR, Miller LM, Dodge, GR, Carey JL, Burdick JA, Mauck RL (2021) Resorbable Pins to Enhance to Retention of Scaffolds in a Porcine Chondral Defect Model. Cartilage. In Press. (Link)

15.  Bansal S, Miller LM, Patel JM, Meadows K, Eby MR, Saleh KS, Martin AR, Stoeckl BD, Hast M, Elliot DM, Zgonis MH, Mauck RL (2020) Transection of the Medial Meniscus Anterior Horn Results in Cartilage Degeneration and Meniscus Remodeling in a Large Animal Model. Journal of Orthopaedic Research. 38(12):2696-2708. (Link)

14.  Patel JM, Brzezinski A, Ghodbane SA, Tarapore R, Lu T, Gatt CJ, Dunn MG (2020) Personalized Fiber Reinforcement Networks for Meniscus Reconstruction. Journal of Biomechanical Engineering. 142(5):051008. (Link)

13. Patel JM, Wise BC, Bonnevie ED, Mauck RL (2019) A Systematic Review and Guide to Mechanical Testing for Articular Cartilage Tissue Engineering. Tissue Engineering Part C. 25(10):593-608. (Link)

12.  Martin AR, Patel JM, Zlotnick HM, Carey JL, Mauck RL (2019) Emerging Therapies for Cartilage Regeneration in Currently Excluded ‘Red Knee’ Populations. Nature Published Journals Regenerative Medicine. 4(1): 1-12. (Link)

11.  Ghodbane SA, Patel JM, Brzezinski A, Lu TM, Gatt CJ, Dunn MG (2019) Biomechanical Characterization of a Novel Collagen Infused 3D Printed Polymer Scaffold for Partial Meniscus Replacement. J Biomed Mater Res B. 107(8):2457-2465. (Link)

10.  Patel JM, Saleh KS, Burdick JA, Mauck RL (2019) Bioactive Factors for Cartilage Repair and Regeneration: Improving Delivery, Retention, and Activity. Acta Biomateriala. 93: 222-238. (Link)

9.  Ghodbane SA, Brzezinski A, Patel JM, Pfaff WH, Marzano KN, Gatt CJ, Dunn MG (2019) Partial Meniscus Replacement with a Collagen-Hyaluronan Infused Three-Dimensional Printed Polymeric Scaffold. Tissue Eng Par A. 25(5-6): 379-389. (Link)

8.  Patel JM, Brzezinski A, Raole DA, Dunn MG, Gatt CJ (2018) Interference screw versus suture endobutton fixation of a fiber-reinforced meniscus device. Am J Sports Med. 46(9): 2133-2141. (Link)

7.  Patel JM, Ghodbane SA, Brzezinski A, Gatt CJ, Dunn MG (2018) Tissue-engineered total meniscal replacement using a fiber-reinforced scaffold in a two-year ovine model. Am J Sports Med. 46(8): 1844-1856. (Link)

6.  Patel JM, Jackson RC, Schneider GL, Ghodbane SA, Dunn MG (2018) Carbodiimide cross-linking counteracts the detrimental effects of gamma irradiation on the physical properties of collagen-hyaluronan sponges. J Mater Sci Mater Med. 29(6):75. (Link)

5.  Brzezinski A*, Ghodbane SA*, Patel JM*, Perry BA, Gatt CJ, Dunn MG (2017) The Ovine Model for Meniscus Tissue Engineering: Considerations of Anatomy, Function, Implantation, and Evaluation. Tissue Eng Part C. 23(12):829-841. (Link)

4.  Patel JM, Merriam AR, Kohn J, Gatt CJ, Dunn MG (2016) Negative Outcomes of Poly(l-Lactic Acid)Fiber-Reinforced Scaffolds in an Ovine Total Meniscus Replacement Model. Tissue Eng Part A. 22(17-18):1116-1125. (Link)

3.  Patel JM, Merriam AR, Culp BM, Gatt CJ, Dunn MG (2016) One-year Outcomes of Total Meniscus Reconstruction Using a Novel Fiber-Reinforced Scaffold in an Ovine Model. Am J Sports Med. 44(4):898-907. (Link)

2.  Merriam AR, Patel JM, Culp BM, Gatt CJ, Dunn MG (2015) Successful Total Meniscus Reconstruction Using a Novel Fiber Reinforced Scaffold: a 16 and 32 Week Study in an Ovine Model. Am J Sports Med. 43(10):2528-37. (Link)

1.  Wijeratne SS, Botello E, Yeh H-C, Zhou Z, Bergeron AL, Frey EW, Patel JM, Nolasco L, Turner NA, Moake JL, Dong J-F, Kiang C-H (2013) Mechanical Activation of a Multimeric Adhesive Protein Through Domain Conformational Change. Phys Rev Lett. 110:108102. (Link)

Intellectual Property (Patents)

3. Patel JM, Labib S, Myers DR, Hasson M, Fernandes LM. “Compositions and Methods for Improving Cartilage Formation.” International PCT Application No. PCT/US23/29495. August 4, 2023. (Emory OTT Link) (Google Patents)

2.  Patel JM, Loebel C, Martin AR, Mauck RL, Burdick JA. “Systems for Targeted Tissue BioSealing or Repair.” International PCT Application No. WO/2020/014623. January 16, 2020. (Link)

1.  Patel JM, Dunn MG, Gatt CJ. “System and method for making personalized fibrocartilage implants.” International PCT Application No. WO/2017/095662 A1. June 8, 2017. (Link)

Book Chapters

4. Kowalski M, Hasson M, Hammond KE, Labib S, Patel JM. “Biomaterials in Connective Tissue Regeneration and Rehabilitation.” Regenerative Rehabilitation – From Basic Science to the Clinic. 2022. ISBN 978-3-030-95883-1. pp 291-330. (Link)

3.  Ekwueme EC, Patel JM, Freeman JW, Danti S. “Applications of Bioresorbable Polymers in the Skeletal Systems (Cartilages, Tendons, Bones).” Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine. 2017, ISBN:9780081002667. pp391-422. (Link)

2.  Patel JM, Dunn MG. “Cartilage Tissue Engineering”. Regenerative Engineering of Musculoskeletal Tissues and Interfaces. 1st edition. 2015, ISBN: 9781782423010. pp135-160. (Link)

1.  Wijeratne SS, Patel JM, Kiang C-H. “Melting Transitions of DNA-Capped Gold Nanoparticle Assemblies”. Reviews in Plasmonics 2010. 2010, ISBN 978-1-4614-0883-3. pp269-282. (Link)